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Laboratory of Pharmacognosy
Research Overview
There are several research projects for pharmacognogy and
herbal medicine. Our major projects are on the origin and
chemical constituents of natural medicine, isolation of various
bioactive components from Umbeliferous and Araliaceous crude
drugs constituents, and application for development of natural
medicine. The study on the chemical constituents of natural
medicine focuses especially on triterpene constituents. The
physicochemical specifications of herbal medicine are also
our interest.
Ongoing Projects
The studies on the triterpenoidal constituents of leaves of
Acanthopanax divaricatus forma flavi -flos
The preparation of chemical reference standard from natural
medicine,- triterpenoidal constituents of leaves of Acanthopanax
koreanum and Acanthopanax sieboldanumi
A Study on the origin of Polygonatum spp. on the market of
herbal medicine.
A Study on the constituents of Angelica pebescense var. biserata
Medicinal Plant Garden
The Medicinal Plant Garden, initially established in 1955,
was located near the College of Pharmacy building. In 2003,
the Medicinal Plant Garden moved to Seocho-gu, Seoul, with
more than 500 species of plants in about 700 square meters.
The major role of the garden is to keep the species of medicinal
plants and provide plant samples for research.
□ Natural Product Chemistry Lab
Director: Professor Seon-Pyo Hong (seonhong@khu.ac.kr)
Research Overview
Our main research focuses on the development of anticancer
agents using herbal medicine, the development of unique diagnostic
method for reducing sugars and the separation of natural products.
Through these research projects, we hope to achieve the popularization
and scientification of Oriental medicines.
Ongoing Projects
Development of Anticancer Agent from the Preparation of Oriental
Medical Extracts
Development of New Diagnostic Method for Galactosemia
□ Oriental Herbal Pharmacology and
Herbal Prescription Laboratory
Director: Professor Jong Hoon Ryu, Ph.D. (jhryu63@khu.ac.kr)
Research Overview
The Laboratory of Herbal Pharmacology and Herbal Prescription
is focused on the pharmacological effects of various herbal
materials and herbal prescriptions which are traditionally
established. At first, we are interested in the anxiolytic
and anti-depression drugs from those materials. Secondly,
we endeavor to search for new drugs from the herbal materials
and herbal prescriptions for the ischemic stroke. Moreover,
we have investigated the various properties of some single
compounds which should be useful for memory deterioration.
The ongoing projects are supported by the Korean Government
and pharmaceutical companies.
Ongoing Projects
Development of food and medicinal substances possessing anti-depressive
effects from natural herbal materials
A Study on Hwang-Ryun-Hae-Dok-tang and Its Modified Agent
on the Transient
Ischemic Rat Model.
Memory-related experiments using the active compound isolated
from the natural herbal materials
□ Oriental Herbology Laboratory
Research Overview
Our research at the Oriental Herbology Laboratory focuses
on the study of the origin, appraisal, efficacy, clinical
application and processing of medicinal materials such as
plants, animals and minerals. Our lab not only conducts research
on the origins and efficacy of the medicinal materials recorded
in the classic but also accesses the prescriptive theories.
□ Oriental Physiology Laboratory
Research Overview
Under the motto of 'the Creation of the Third Medicine', the
Dept. of Physiology conducts research in vital phenomena,
which are the object of Oriental Pharmaceutical Science. For
this purpose, researchers reconfirm the Yin-Yang and Five
elements theory and apply this theory to the up-to-date experiments
so as to establish the base of every field of Oriental Pharmaceutical
Science and direct its future.
□ Laboratory of Biopharmaceutics
Director: Professor Young-Joo Lee, Ph.D.
URL: http://biopharm.khu.ac.kr
Research Overview
Biopharmaceutics aims to ensure that the active substances
are being released in the appropriate amounts and with the
expected speed at the right locations so as to optimize the
effect in the body while minimizing the side effects.
The research focus of the Laboratory of Biopharmaceutics is
to understand the process of drug absorption, distribution,
metabolism and elimination. We are especially focused on the
Blood-brain barrier & Blood-cerebrospinal barrier, Herb-Drug
interaction, Evaluation of Bioavailability and Bioequivalence
and related statistical analysis.
Ongoing Projects
The role of transporters in drug absorption, distribution,
metabolism and elimination
Transporter mediated Herb-Drug interaction
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